Commercial disinfecting wipes generate single-use nonwoven substrate waste that is not currently recyclable or biodegradable under standard landfill conditions in most Canadian jurisdictions. Their environmental footprint relative to liquid concentrate programs depends heavily on which alternative is used for comparison and whether the full program cost, including secondary materials, transport, and water use, is included. Buyers can meaningfully reduce the environmental impact of their wipe program through format selection, right-sizing to surface area, substrate quality optimization, and Canadian sourcing.